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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6dfdefd2e2805fc3f34215f774581ad1b072a3964e5dd8a5154158d58ce6366' 
  AND token = 'PGo5PgMMY/UM22KkkgJ/T+IlPJp1ak8Dllck30bytQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}