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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43da4053e5fe1e599578873f8414ed1fe3f661538e9dc3cecfb92a3cfc3f81fb' 
  AND token = 'TQcyLWKR/EEx0F9fzwGgP2uHq3vbgFV0m9ID8qZ60Us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}