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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bcddb578a792e46ff05af2b4224895b5c7f4dbfa65d83f1123121529def5ce8' 
  AND token = 'p/XbQkYyXXf86QnzEc1vh7nsSsAfh5otl4WvjpDYRRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}