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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e2ea0128fcd6d60d6e1edfd73272e85a12e7eed94af52927dcd668744bad3ad' 
  AND token = 'R9OPzJPoTDDbdHh/yEq0dwSCA2SjUYIyi7zSqInzqoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00447

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}