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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6429f1f84eb976e57300f3de9da3f25696122f5a788524d9f2f99847a0592464' 
  AND token = 'UvKkCET/wL8NmwEEWemdkMiWOwdx91oC/079YT4HJPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}