SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00638a03d2b0f7fea9f8b6eed336048f071c22e9705c3e6de1e3996db850f7fe' 
  AND token = 'JUw+DKu9+HevktvsBBEDOw69sVDxMMK7XOa2jIK+UWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}