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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '176f317dc3eb295a196bebd8f29b6d7cb0c3f1c57bb6e36c1fafcaede0b8b292' 
  AND token = '+2F+NGgFBETz2IAJim/bPbDF4/cG3OYFA2hOtiPKueA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}