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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f446ee1361133fde347b4525c746dcd03ee1c6f3a34c431d9c4a1eb2171f63b' 
  AND token = 'e4LuAUrTpEi7mDlZxXLdiFIPPtrsmmJHJukOuKZcli8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}