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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff6348b2bae89487743e71dc3a3393f887f46a77ea49e9f659f303786062d210' 
  AND token = 'KR9cKw5r1l934yu7fFg3kUMRB7pST8bVbMjTxz/jrls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}