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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de002660da49f5bb66e654478c0c6382e2fc0c068bb1fcbccde79e717f8c6455' 
  AND token = 'BrJ7Tj/5U8KPWd57e/Wapv4oy6j63qGf4SzRW3v93C0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}