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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7fe5eeef70d97593415d05abf34808a21b746d188b612d07e97b809b122154d' 
  AND token = '3hv8//eeYV1arI/DaUWPs+QN9qGWwv6OsMnzU+wC5DM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}