SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '245dc6e326693c82ce8ce3ef9e5da7fd641ca12c00e192a4e7cb49be27544b9a' 
  AND token = 'PGkEqglXYqWbAUA+DJH3VJl51vGiOWLrJL/3jeMsAhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}