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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d80a7ad3d0d52ab743622f74456fa95a4dd42f6d35ab696c369e2740117b693' 
  AND token = 'jTkmnN28RGBI07NbEe5E1RTZynPnMXKAS1x0vOYXr2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00082

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}