SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caa506c7ee0a898b361848e229d98958e26d2074fd379411cac911ebab635f5b' 
  AND token = 'gHN5d8YI5EAzO0sahe/CESC+EKVKk9LlAkcg9+rKM6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}