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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '456470ac904773536355a7f73e11b42f3aaa1943cb51413f2292b8b9bdd2badc' 
  AND token = 'RDH3e5TTV7AHdirixZVnjEyHnLrvZCsUw2tg4kb6wSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}