SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '587f2cfc000fc42dde3d4c3e20cd9bccd7ad8af12680111acfaa4990bc7899d5' 
  AND token = 'Odo/fpN14GMaT2fq4ddTpK08gqIpGP0mto22pGnq0Xc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}