SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab5fcd6a377de6f7e7aa5fb7460d3bc3a715f71a66f57ab60e4231b523240205' 
  AND token = 'KutMOeWXbNqfIbvKeoeUcGnSA1tiLg//fpSls/DHDDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}