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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '294b5111f716b62095c9bdff962f4556f8f4e6e0492cdd0b09c4e314f01371c9' 
  AND token = 'QTmLSascJKaLIbSBUb6HLAMT9S0EybUnkzmpWHS3tAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}