SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41f6ed4c912620c9c4fbfdacbbd2890faa8fa5c5fa335c99f3a506be787dac9f' 
  AND token = 'YFPb7nkDl333KkIpHucX3F4avdMs2O/rZ1Ww/5cgnZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}