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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2563f2034b1812172f47cd4ccbc38d34c677377b6cca0280741064199449440' 
  AND token = 'GEu/VCpOCJ3cWRvd/B0x/RqrFL/+v+lc6iFQahLWuP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}