SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '551671530af5126825c962bd9e6cb1549f82633399a8f4a105d8ad70d6f21cf1' 
  AND token = '901m/KjY3T4tk4nDhVZdYUjf5n47KyvpddR6WUXF7co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}