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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3adc8ff2ea68c31932d6cf6d66b902dd3edad27bfd26b4de34e1442311c86491' 
  AND token = 'nE2O2L1Vf2tqA+2fOD9aZvxLZ+7IZTMo+9TkyZ1788E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}