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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19df20593235ad7d5754321517e4a6b78c0a66c80ba470ddbe20cd2f576cef50' 
  AND token = 'cUuJP6+kvXVWaEKYKZeFQ3DZF6SK4q6KNLk6Mg6KcA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}