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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49dfab8e579d2266c94ea4951fbc1e476d08838a7602aa1fe1f7edd339418697' 
  AND token = 'x722VSUpiPRzYdnaZEsq/bXAT9MVng6waQg2K3AybkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}