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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13a8b70e3fecc2814e1a16c9ddd11bbeeaee7f378c8ec1f5833ad6cb5f47b949' 
  AND token = '0E5+zURXl0s7cZNCWT0ARre28cSowWKhZrXh0LakA6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}