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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34251a2985d82f6e40fa8cf108a85268d43c8c9264068dd11c426d69d701dbb3' 
  AND token = 'w5ii5GW7lJL1QvOAzyhnCP4WmSlgCzJz0n8Wj1GUnUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}