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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39e39a5f155f28f5e1eba3424557f49be22a5c001a82b9f88f79bd759eab5042' 
  AND token = 'YLQDXmRGWZpjYJ5SsmXeSJt4rRiOX8jUaVJAfrFeCnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}