SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fca9a6e8ca86bf7e85f23e930c64b8c1bafa0c364d2cd904a3afadaf40024939' 
  AND token = 'EQPfeoNZ3lH8KOjKDT23LCc/qmp+4xRulGvdH2dPLpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}