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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '543580f952defa5917fbde2dacc03eb6a3ac23530f280c941798790974a33cae' 
  AND token = 'IpoiHXgYi1cXz0mo29a3kLbKgNKbflJD1PpK+yTq07o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}