SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5b21a2b1eee9f6107bc827e3a21722d5151d126717b7b5cec068a36fb0036fe' 
  AND token = 'syMjrUiPXSSDC6B3YllUCkPhmoNhnOJpHnb954jGghI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}