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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68921d14bc8bc819edf177cfb9e19fb36065e390a2a21c2c665aba1aef31acc7' 
  AND token = 'UxziARbgXTDC4cF4QP/LptWxutoC0+MzicxIuq7E1LY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}