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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5abe8d6946141e6782afd32e2a122562ca2f581f18431bbf87941c16407e4a15' 
  AND token = 'Nx8Y9XeacFezlWFhFD0uyC3849MQKkgMg1JSIeQNtK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}