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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '493adb33539a56704120fd86b451d7cd0a24e3b28f2ac992fa3ea4411f52c849' 
  AND token = 't4O6qzw0aOcjkfw3O6KU93DfxGWDUoKY8gKGxnnTE1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}