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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '464d73bafb7ac9a5aa06c86fd131549aa84971df45c6a17a47fdd5b7b9790ada' 
  AND token = 'zY1M3lox6Vzu8bsLXBPnLkq2skj/QoXtLE81KdYbI0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}