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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37f52d518c4957f29a985dc505b7b9c95a47444dd354ce6280984f178a0f24cb' 
  AND token = 'EDmNkHpFuhQSOhCdtCVE5BbTh9yvyuV+fddf8hggV3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}