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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fde7b9cb992070656bc9d0d1ab67eb728db154d4f2ea485b99798c517858b4a7' 
  AND token = 'mEQbXteRexG1UQ8ImbRXWij5veR5PvxfoIhC9pHhvII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}