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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d0a57f8d851bf00beec8e9d51ce267cf18da8d4dda33b9eabd5f1f4035291b5' 
  AND token = 'EE0imMO7onV8v5yZcIs4sMM40SrTqZgFxRaYqSpNwjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}