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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c33efb8ec6a8f9b2040de1955ecd42222785dde288c2dd3763e47d98e53f730' 
  AND token = 'Uo8pGNBUI81hpraJkRpZK341fZ4Tbs9f4/2kA7nzW8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}