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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e9788b6385e3c757c93d11e1d3343d8ff0ef1b331064ba59cf00d5921ada0e7' 
  AND token = 'vKF/NZY46RIMvBAIMJQphSWU9sbPIZ8MsduXIMtY5QI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}