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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3974cc646eaa2b6f42abaa9e150346f1d5fc734e80ca75e86e4f0d466fcc28de' 
  AND token = 'k725pPyPGHw+fLTtzbRFj6NhouFqL3cKOSKT4ytno1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}