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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b049fd08e61cec333434ed84a8cd9b1ff659e4f9ef711a188359ed80217b9d0a' 
  AND token = 'M8abqX1x7mClqQIH1zA0HEYGYaFi7xpsZ+Pkyeucewk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}