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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fd02a415196848a5815f426c33b33fd1570829f446dd80eb163a14d71a9483e' 
  AND token = 'SIdnyJSHD1qSS5zFKZIvJ0SUXSql6Pp+BIQEAlKeAcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}