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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a184275e74faad5b5fc21e6d4b191d4099a805f51caf1ea921b72d4da44df56' 
  AND token = 'Pxs/0zUBj9Y1ms0AuOoJpNwW/pev5d/pxqVpS0Qo7Mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}