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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '757ec3bf175c901980820571df4b0edb23c408e5dcb9d8391c3b596f5b76b830' 
  AND token = 'Kwez76LP+xAFEz5u4MI1jls8zKPicH0wxTE+VEr8UG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}