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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aecceff84cc075e200e8fb052fc965fc78d6c0809a72d9deb3208e858e7df5e' 
  AND token = 'LL7jgSsRkcAJM0HryTVg02bwdQmpHEhv0XodzWEqb8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}