SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e672f67e8a6a1a16931a21138239cf260510ba23a145db86c08ef892b4fe65b' 
  AND token = 'WQFq6IqKxCA5M1sKjQcOmq1TOtwFsvrZeTRhZeDvGkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}