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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e772727098de452222d1a89244677da9ae66b5389a0b6ea4d32ced68b06c78d' 
  AND token = '5l6+xkIV+kXzp7zh/gwxsYTHuLmOdFF60AHhddlULX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}