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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4df54395c9b7801157d70a646d19f5cfe199cfe020db5cc5d53a4ad5cd7ec285' 
  AND token = '8EC+LW9+tqEYdi1nSEVEP9XTAfrFVGwm/EbgptPteJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}