SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfd1520ddd14f000b99c23ca7823ba00c51a793abf394a36f8c69e4fb280448e' 
  AND token = 'bdHTu0uAHKTOM9zhAKWnHTeUM2W2nWIc7t0SjOSnZKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}