SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06791ed230aa38d477d06099cb7c36432cbded98a7bd846677151a75e67b5942' 
  AND token = 'XGS+IuYACeM9fKLnJoEnLP/DEtoXvlbbV8D+Ta2CKv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}